Skip to content
Call Us Now
Safety & Neighborhoods Guide 2026

Safest Neighborhoods
Panama City

Panama City, Panama offers some of the most secure, expat-friendly neighborhoods in Central America — with world-class amenities and a welcoming international community.

Panama City, Panama (not Panama City, Florida) is widely regarded as one of the safest capitals in Latin America for expatriates. While no city is without risk, the expat-popular neighborhoods of Panama City feature 24/7 private security, gated residential towers, well-lit streets, and strong communities of international residents. Understanding which neighborhoods offer the best safety record, infrastructure, and lifestyle for your needs is the first step to a successful relocation.

Ranked by Safety

Safest Neighborhoods for Expats

01

Punta Pacifica

Excellent

Consistently rated the safest neighborhood in Panama City. A gated peninsula with luxury high-rises, private security in every building, and 24/7 CCTV coverage. Home to Johns Hopkins-affiliated Hospital Punta Pacifica, high-end malls, and international restaurants. Virtually zero street crime.

Best For

Families, retirees, executives

02

Costa del Este

Excellent

A master-planned business and residential district in eastern Panama City. Wide, well-lit boulevards, private residential communities, international schools, and corporate office towers. One of the fastest-growing neighborhoods, attracting Panama's upper-middle and upper classes alongside expat families.

Best For

Families, corporate expats

03

Santa María

Excellent

One of Panama's newest master-planned communities, featuring a championship golf course, luxury homes, and condos within a fully gated perimeter. High-end, family-oriented, and extremely secure. Preferred by diplomats and senior executives.

Best For

Luxury buyers, diplomats

04

El Cangrejo

Good

The most walkable, urban expat neighborhood in Panama City. Generally safe during daylight hours with a vibrant street scene, restaurants, and cafés. Standard urban precautions apply at night. Very popular with digital nomads and younger expats for its convenience and social life.

Best For

Digital nomads, young expats

05

San Francisco

Good

A large, established residential district popular with middle-class Panamanians and expats alike. Close to Cinta Costera and Multiplaza. Generally safe, especially in the newer high-rise condo buildings with gated lobbies and security personnel.

Best For

All expats, value buyers

06

Casco Viejo

Improving

Panama's UNESCO World Heritage historic district has undergone major gentrification. The core tourist and expat area around Plaza Bolívar and Calle Uruguay is safe and lively. However, exercise caution near the borders with El Chorrillo neighborhood. Ideal for investors and urban culture enthusiasts.

Best For

Investors, urban explorers

Areas to Approach with Caution

El Chorrillo: Adjacent to Casco Viejo. High crime rates, avoid at night.

Curundú: One of the city's most impoverished areas. Not recommended for expats.

San Miguelito: A large suburban municipality north of the city. Some areas are safe; others require local knowledge.

Tocumen: Area around the international airport — budget hotels, not a residential recommendation.

Safety Tips for Expats in Panama City

Live in buildings with 24/7 security and access control — most mid-to-high-end condos offer this.

Use Uber or InDriver for transportation — taxis hailed on the street carry more risk.

Be discreet with valuables, laptops, and smartphones in public spaces.

Join local expat Facebook groups (Panama Expats, Panama City Social Club) for real-time safety updates.

Register with the US Embassy in Panama for travel alerts and emergency assistance.

Trust your instincts — if a street or situation feels off, move on.

Find Your Safe Panama City Home

Browse properties in Panama City's safest, most expat-friendly neighborhoods — curated for international buyers and renters.